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\u8d5e\u52a9\u5185\u5bb9<\/span><\/i><\/b><\/p>\n

\u80a5\u80d6\u7387\u7684\u4e0a\u5347\u4ee3\u8868\u4e86\u5f53\u4eca\u91cd\u5927\u5065\u5eb7\u6311\u6218,\u4e0e\u5305\u62ec 2 \u578b\u7cd6\u5c3f\u75c5\u5728\u5185\u7684\u4f17\u591a\u6162\u6027\u75be\u75c5\u6709\u5173\u3002\u968f\u7740\u80a5\u80d6\u548c\u7cd6\u5c3f\u75c5\u53d8\u5f97\u66f4\u52a0\u666e\u904d,\u6709\u6548\u7684\u4f53\u91cd\u7ba1\u7406\u548c\u7cd6\u5c3f\u75c5\u62a4\u7406\u4e4b\u95f4\u7684\u8054\u7cfb\u53d8\u5f97\u8d8a\u6765\u8d8a\u6e05\u6670\u3002\u867d\u7136\u996e\u98df\u8c03\u6574\u548c\u4f53\u529b\u6d3b\u52a8\u5bf9\u4e8e\u63a7\u5236\u7cd6\u5c3f\u75c5\u548c\u4f53\u91cd\u81f3\u5173\u91cd\u8981,\u4f46\u836f\u7269\u5728\u89e3\u51b3\u8fd9\u4e9b\u76f8\u4e92\u5173\u8054\u7684\u95ee\u9898\u65b9\u9762\u7684\u91cd\u8981\u6027\u6b63\u53d7\u5230\u66f4\u591a\u5173\u6ce8\u3002 <\/strong><\/p>\n

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\u7cd6\u5c3f\u75c5\u836f\u7269\u53ca\u5176\u5bf9\u4f53\u91cd\u7684\u5f71\u54cd<\/b><\/h2>\n

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\u7cd6\u5c3f\u75c5\u836f\u7269\u6982\u8ff0<\/span><\/h3>\n

\u7d20(Insulin):\u80f0\u5c9b\u7d20\u7597\u6cd5\u4f20\u7edf\u4e0a\u7528\u4e8e\u63a7\u5236\u8840\u7cd6,\u53ef\u5bfc\u81f4\u67d0\u4e9b\u4e2a\u4f53\u4f53\u91cd\u589e\u52a0,\u8fd9\u4e3b\u8981\u662f\u7531\u4e8e\u5176\u5c06\u8461\u8404\u7cd6\u4f5c\u4e3a\u8102\u80aa\u50a8\u5b58\u7684\u4f5c\u7528,\u8fd9\u5bf9\u90a3\u4e9b\u8bd5\u56fe\u51cf\u80a5\u7684\u4eba\u6765\u8bf4\u53ef\u80fd\u9002\u5f97\u5176\u53cd\u3002<\/span><\/p>\n

GLP-1\u53d7\u4f53\u6fc0\u52a8\u5242:\u50cf\u5229\u62c9\u9c81\u80bd\u548c\u7d22\u9a6c\u9c81\u80bd\u8fd9\u6837\u7684\u836f\u7269\u5c5e\u4e8e\u8fd9\u4e00\u7c7b,\u5b83\u4eec\u6a21\u4effGLP-1\u6fc0\u7d20\u7684\u4f5c\u7528,\u523a\u6fc0\u80f0\u5c9b\u7d20\u5206\u6ccc,\u964d\u4f4e\u98df\u6b32,\u4e34\u5e8a\u7814\u7a76\u8868\u660e,\u8fd9\u4e9b\u836f\u7269\u53ef\u4ee5\u5bfc\u81f4\u4f53\u91cd\u663e\u7740\u51cf\u8f7b,\u4f7f\u5176\u6210\u4e3a\u6cbb\u7597\u7cd6\u5c3f\u75c5\u548c\u80a5\u80d6\u75c7\u60a3\u8005\u7684\u70ed\u95e8\u9009\u62e9\u3002<\/span><\/p>\n

SGLT2\u6291\u5236\u5242:\u6069\u683c\u5217\u51c0\u548c\u5361\u683c\u5217\u51c0\u7b49\u836f\u7269\u901a\u8fc7\u963b\u6b62\u80be\u810f\u4e2d\u7684\u8461\u8404\u7cd6\u91cd\u5438\u6536,\u5bfc\u81f4\u5c3f\u6db2\u4e2d\u7684\u8461\u8404\u7cd6\u6392\u6cc4\u589e\u52a0\u800c\u53d1\u6325\u4f5c\u7528,\u9664\u4e86\u5176\u964d\u8840\u7cd6\u4f5c\u7528\u5916,\u8fd9\u4e9b\u836f\u7269\u8fd8\u4e0e\u901a\u8fc7\u8461\u8404\u7cd6\u635f\u5931\u70ed\u91cf\u800c\u9002\u5ea6\u51cf\u80a5\u6709\u5173\u3002<\/span><\/p>\n

\u4f5c\u7528\u673a\u5236\u53ca\u5176\u5bf9\u4f53\u91cd\u7684\u5f71\u54cd<\/span><\/h3>\n

GLP-1\u53d7\u4f53\u6fc0\u52a8\u5242,\u5c24\u5176\u56e0\u5176\u5728\u63a7\u5236\u7cd6\u5c3f\u75c5\u548c\u4fc3\u8fdb\u51cf\u80a5\u65b9\u9762\u7684\u53cc\u91cd\u4f5c\u7528\u800c\u83b7\u5f97\u5173\u6ce8,\u5b83\u4eec\u6709\u52a9\u4e8e\u8c03\u8282\u98df\u6b32,\u5bfc\u81f4\u70ed\u91cf\u6444\u5165\u51cf\u5c11,\u968f\u540e\u4f53\u91cd\u51cf\u8f7b,\u6b64\u5916,\u5b83\u4eec\u51cf\u7f13\u80c3\u6392\u7a7a,\u8fd9\u6709\u52a9\u4e8e\u996d\u540e\u9971\u8179\u611f\u3002<\/span><\/p>\n

SGLT2\u6291\u5236\u5242,\u867d\u7136\u4e3b\u8981\u5173\u6ce8\u8461\u8404\u7cd6\u7ba1\u7406,\u4f46\u4e5f\u6709\u5229\u5c3f\u4f5c\u7528,\u53ef\u56e0\u6db2\u4f53\u6d41\u5931\u800c\u5bfc\u81f4\u521d\u59cb\u4f53\u91cd\u51cf\u8f7b,\u4f46\u957f\u671f\u4f7f\u7528\u53ef\u80fd\u6709\u52a9\u4e8e\u66f4\u53ef\u6301\u7eed\u7684\u4f53\u91cd\u7ba1\u7406,\u56e0\u4e3a\u8eab\u4f53\u8102\u80aa\u51cf\u5c11\u3002<\/span><\/p>\n

\u4f7f\u7528\u7cd6\u5c3f\u75c5\u836f\u7269\u51cf\u80a5\u7684\u597d\u5904<\/b><\/h2>\n

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\u53cc\u91cd\u597d\u5904:\u5728\u51cf\u80a5\u7684\u540c\u65f6\u63a7\u5236\u7cd6\u5c3f\u75c5<\/span><\/h3>\n

\u901a\u8fc7\u4f7f\u7528\u4fc3\u8fdb\u51cf\u80a5\u7684\u7cd6\u5c3f\u75c5\u836f\u7269,\u4e2a\u4eba\u53ef\u4ee5\u540c\u65f6\u89e3\u51b3\u4e24\u4e2a\u5173\u952e\u7684\u5065\u5eb7\u95ee\u9898\u3002\u8fd9\u79cd\u53cc\u91cd\u65b9\u6cd5\u53ef\u4ee5\u6539\u5584\u4ee3\u8c22\u5065\u5eb7,\u51cf\u5c11\u5bf9\u989d\u5916\u836f\u7269\u7684\u9700\u6c42,\u5e76\u964d\u4f4e\u4e0e\u7cd6\u5c3f\u75c5\u548c\u80a5\u80d6\u76f8\u5173\u7684\u5e76\u53d1\u75c7\u7684\u98ce\u9669\u3002<\/span><\/p>\n

\u51cf\u80a5\u7684\u5fc3\u7406\u548c\u60c5\u611f\u76ca\u5904<\/span><\/h3>\n

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\u4e34\u5e8a\u7814\u7a76\u7684\u8bc1\u636e<\/span><\/h3>\n

GLP-1\u53d7\u4f53\u6fc0\u52a8\u5242\u548cSGLT2\u6291\u5236\u5242\u5728\u4fc3\u8fdb2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u4f53\u91cd\u51cf\u8f7b\u65b9\u9762\u7684\u6709\u6548\u6027,\u4f8b\u5982,\u7814\u7a76\u8868\u660e,\u4e0e\u6807\u51c6\u7cd6\u5c3f\u75c5\u6cbb\u7597\u7684\u60a3\u8005\u76f8\u6bd4,\u4f7f\u7528\u7d22\u9a6c\u9c81\u80bd\u7684\u60a3\u8005\u5e73\u5747\u4f53\u91cd\u51cf\u8f7b\u8d85\u8fc715%,\u8fd9\u79cd\u5927\u5e45\u5ea6\u4f53\u91cd\u51cf\u8f7b\u53ef\u4ee5\u5e26\u6765\u66f4\u597d\u7684\u8840\u7cd6\u63a7\u5236\u548c\u6574\u4f53\u5065\u5eb7\u7ed3\u679c\u3002<\/span><\/p>\n

\u8003\u8651\u56e0\u7d20\u548c\u6311\u6218<\/b><\/h2>\n

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\u6f5c\u5728\u7684\u526f\u4f5c\u7528\u548c\u98ce\u9669<\/span><\/h3>\n

\u6bcf\u79cd\u836f\u7269\u90fd\u6709\u53ef\u80fd\u5f15\u8d77\u526f\u4f5c\u7528\u3002\u4f8b\u5982,GLP-1 \u53d7\u4f53\u6fc0\u52a8\u5242\u4f1a\u5bfc\u81f4\u6076\u5fc3\u548c\u8179\u6cfb\u7b49\u80c3\u80a0\u9053\u95ee\u9898,\u8fd9\u53ef\u80fd\u4f1a\u963b\u6b62\u4e00\u4e9b\u60a3\u8005\u575a\u6301\u6cbb\u7597\u3002\u540c\u6837,SGLT2 \u6291\u5236\u5242\u53ef\u80fd\u4f1a\u56e0\u5c3f\u6db2\u4e2d\u8461\u8404\u7cd6\u6c34\u5e73\u5347\u9ad8\u800c\u5bfc\u81f4\u8131\u6c34\u548c\u5c3f\u8def\u611f\u67d3\u3002\u56e0\u6b64,\u60a3\u8005\u4e0e\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u5c31\u8fd9\u4e9b\u6f5c\u5728\u526f\u4f5c\u7528\u8fdb\u884c\u516c\u5f00\u5bf9\u8bdd\u4ee5\u786e\u5b9a\u6700\u9002\u5408\u5176\u4e2a\u4eba\u60c5\u51b5\u7684\u836f\u7269\u81f3\u5173\u91cd\u8981\u3002<\/span><\/p>\n

\u533b\u7597\u76d1\u7763\u7684\u91cd\u8981\u6027<\/span><\/h3>\n

\u4f7f\u7528\u7cd6\u5c3f\u75c5\u836f\u7269\u51cf\u80a5\u5e94\u6210\u4e3a\u7531\u533b\u7597\u4fdd\u5065\u4e13\u4e1a\u4eba\u5458\u76d1\u7763\u7684\u7efc\u5408\u6cbb\u7597\u8ba1\u5212\u7684\u4e00\u90e8\u5206\u3002\u4e2a\u4eba\u5bf9\u836f\u7269\u7684\u53cd\u5e94\u53ef\u80fd\u5dee\u5f02\u5f88\u5927,\u9700\u8981\u4e2a\u6027\u5316\u8c03\u6574\u548c\u76d1\u6d4b\u3002<\/span><\/p>\n

\u751f\u6d3b\u65b9\u5f0f\u7684\u6539\u53d8\u4f5c\u4e3a\u4e00\u79cd\u8865\u5145\u65b9\u6cd5<\/span><\/h3>\n

\u867d\u7136\u836f\u7269\u53ef\u4ee5\u5e2e\u52a9\u4f53\u91cd\u7ba1\u7406,\u4f46\u4e0e\u751f\u6d3b\u65b9\u5f0f\u6539\u53d8\u76f8\u7ed3\u5408\u65f6\u6548\u679c\u6700\u597d\u3002\u5747\u8861\u996e\u98df\u3001\u5b9a\u671f\u4f53\u529b\u6d3b\u52a8\u548c\u884c\u4e3a\u6539\u53d8\u53ef\u4ee5\u63d0\u9ad8\u7cd6\u5c3f\u75c5\u836f\u7269\u7684\u6709\u6548\u6027,\u4ece\u800c\u5e26\u6765\u66f4\u53ef\u6301\u7eed\u7684\u51cf\u80a5\u6548\u679c\u3002<\/span><\/p>\n

\u7ed3\u8bba<\/b><\/h2>\n

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GLP-1\u53d7\u4f53\u6fc0\u52a8\u5242\u548cSGLT2\u6291\u5236\u5242\u5728\u4fc3\u8fdb2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u4f53\u91cd\u51cf\u8f7b\u65b9\u9762\u7684\u6709\u6548\u6027,\u4f8b\u5982,\u7814\u7a76\u8868\u660e,\u4e0e\u6807\u51c6\u7cd6\u5c3f\u75c5\u6cbb\u7597\u7684\u60a3\u8005\u76f8\u6bd4,\u4f7f\u7528\u7d22\u9a6c\u9c81\u80bd\u7684\u60a3\u8005\u5e73\u5747\u4f53\u91cd\u51cf\u8f7b\u8d85\u8fc715%,\u8fd9\u79cd\u5927\u5e45\u5ea6\u4f53\u91cd\u51cf\u8f7b\u53ef\u4ee5\u5e26\u6765\u66f4\u597d\u7684\u8840\u7cd6\u63a7\u5236\u548c\u6574\u4f53\u5065\u5eb7\u7ed3\u679c\u3002 \u8003\u8651\u56e0\u7d20\u548c\u6311\u6218 \u867d\u7136\u7cd6\u5c3f\u75c5\u836f\u7269\u5728\u4f53\u91cd\u7ba1\u7406\u4e2d\u7684\u597d\u5904\u4ee4\u4eba\u4fe1\u670d,\u4f46\u4ecd\u9700\u8981\u7262\u8bb0\u91cd\u8981\u7684\u8003\u8651\u56e0\u7d20\u3002 \u6f5c\u5728\u7684\u526f\u4f5c\u7528\u548c\u98ce\u9669 \u6bcf\u79cd\u836f\u7269\u90fd\u6709\u53ef\u80fd\u5f15\u8d77\u526f\u4f5c\u7528\u3002\u4f8b\u5982,GLP-1 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