Italy will lift quarantine restrictions for travellers arriving from European and Schengen zone countries, Britain and Israel from May 16, the Health Ministry said on Friday.
People entering Italy from these areas currently face five days of quarantine and mandatory testing both before arrival and at the end of their isolation period.
A negative swab before travelling will still be required, the Ministry said in a statement.
It added that current restrictions for people travelling from Brazil would be maintained.
Quarantine requirement may be scrapped for those arriving from the United States from June, Di Maio said, after meeting Health Minister Roberto Speranza to discuss the easing of restrictions for countries where vaccination levels are high.
Italy has registered 122,694 deaths linked to COVID-19 since the outbreak began last year, the second-highest toll in Europe after Britain and the seventh-highest in the world. The country has reported 4.1 million cases to date.